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Key: test item, instrument name, total nonvolatile migration, gravimeter, moisture permeameter
Loss on drying
Release time:
2021-08-05
Pharmaceuticals is a very rigorous process, and the quality of raw materials has a major impact on the quality of pharmaceuticals. In this regard, the state has formulated a number of testing items to identify the quality of raw materials, and "loss on drying" is one of them.
According to the pharmacopoeia, take about 1g or the weight specified under each item, place it in a flat weighing bottle that is dried to a constant weight under the same conditions as the test product, and accurately weigh it. Unless otherwise specified, dry at 105℃ to a constant weight. Calculate the loss on drying of the test product from the lost weight and the sample volume.
Ovens and balances are routine instruments in the laboratory. The experimental process is not difficult at first glance, but it is always tricky in actual work. First of all, a 1g sample often contains very little water, and it is easily affected by environmental humidity when the experimenter manually operates it. In addition, according to the requirements of the pharmacopoeia, the difference in weighing after 2 times of drying is less than 0.3mg for a constant weight. This puts forward higher requirements for manual operation, so it often takes a long time for experimenters to complete the experiment, and it even appears that the quality after drying is heavier than the quality before drying.
Is there an easier way to detect this item? The answer is yes-Constant Weight Tester.
The constant weight instrument developed and designed by Xitang Technology specifically to meet the requirements of constant weight, integrates heating and drying, drying and cooling, constant temperature weighing and other functions. Instead of traditional ovens, drying ovens and balances, two weighing processes can achieve constant weight weighing. It not only perfectly meets the requirements of the standard 100%, but also greatly improves the efficiency of constant weight and the accuracy of the experiment.
At this point, the "loss on drying" experiment does not need to waste more time, the experimenter only needs to load the sample, and the rest is handed over to the automation. At present, more than ten listed pharmaceutical companies have applied the constant weight instrument for quality inspection.
In addition, the constant weight meter is also equipped with a water bath function. In addition to the drying weight loss test, it can also be used for: non-volatile matter in purified water, non-volatile matter in extracts of medicine packaging materials, extracts of traditional Chinese medicines and other experiments that require constant weight.
Loss on Drying Constant Weight——Relative Products:
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Related Applications
Evaporating Residue, Non-volatile Residue
2021-09-01
Pharmacy is a very rigorous process, and the quality of water has a major impact on the quality of pharmaceuticals. Ordinary water contains many trace elements and other substances, which cannot meet the needs of pharmaceutical production. Only purified water that meets the requirements can be used in pharmaceutical production. In this regard, the state has formulated a number of testing items to monitor the quality of purified water, and "non-volatile matter" is the most "torturing" item. The "most tortured" person in non-volatile matter testing? According to the Pharmacopoeia, 100ml of purified water is placed in an evaporating dish with constant weight to evaporate to dryness, and after drying to constant weight, the remaining residue shall not exceed 1mg; in addition, according to the general requirements of the Pharmacopoeia, the constant weight needs to be dried twice and weighed. The difference is less than 0.3mg. The 0.3mg constant weight requirement is very difficult for manual operation, so too many experimenters always struggle with this, and they think that the non-volatile item is too torturous. How to solve this "torture" problem? In today's increasingly high degree of automation, Xitang Technology has given the answer-a non-volatile constant weight meter. The constant weight instrument developed and designed by Xitang specifically to meet the requirements of constant weight, integrates the functions of water bath evaporation, heating and drying, drying and cooling, and constant temperature weighing. Instead of traditional water bath, oven, drying oven and balance, 2 weighing processes can achieve constant weight weighing. It not only perfectly meets the requirements of the standard 100%, but also greatly improves the efficiency of constant weight and the accuracy of the experiment. At this point, the "torturing" experiment is no longer tortured, the experimenter only needs to install the sample, and the rest is handed over to the automation. At present, more than ten listed pharmaceutical companies have applied the constant weight instrument for quality inspection. The constant weight instrument in the pharmaceutical industry can also be applied to: non-volatile matter in extracts of pharmaceutical packaging materials, loss on drying of raw materials, extracts of traditional Chinese medicines, and other constant weight requirements experiments. Purified Water Non-volatile Residue Constant Weight Tester——Relative Products： Constant Weight Tester 12 specimens, integrated the functions of evaporating, heating, drying, constant temperature weighing. Constant Weight Tester 23 specimens, integrated the functions of evaporating, heating, drying, constant temperature weighing. Constant Weight Tester 48 specimens, integrated the functions of evaporating, heating, drying, constant temperature weighing. Constant Weight Tester 12 specimens, integrated the functions of heating, drying, constant temperature weighing.
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