Key: test item, instrument name, total nonvolatile migration, gravimeter, moisture permeameter

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Water Bath Constant‑Weight Analyzer for Total Migration & Loss on Drying

ERT- 121 /181/ 231 -C
Focusing on packaging and material testing technology, we are committed to quality control in industries such as healthcare, pharmaceuticals, food, packaging, textiles, and new materials. Our products are widely used in enterprises, testing institutions, universities, and research institutes.
  • Description
  • Applications
  • Standard
  • Features
  • Parameter
  • Configuration
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    • Commodity name: Water Bath Constant‑Weight Analyzer for Total Migration & Loss on Drying

    ERT- 121 /181/ 231 -C

    Water Bath Constant‑Weight Analyzer for Total Migration & Loss on Drying

                                      Automated Evaporation‑Drying‑Weighing Workstation - Model ERT‑C Series

     

    Overview

    The LabStone ERT‑C Series​ is a fully automated workstation designed specifically for total migration testing of food contact materials, non‑volatile residue determination, and loss on drying / moisture analysis. It replaces the traditional, labor‑intensive workflow of water baths, drying ovens, desiccators, and analytical balances with a single, compliant, and unattended process.
    Engineered for pharmaceutical, food contact material, and contract testing laboratories, the ERT‑C Series ensures pharmacopoeia‑grade constant‑weight results​ with high throughput and minimal operator intervention.

     

    Key Applications

    Food Contact Materials (Total Migration)

    • Gravimetric determination of total migration from plastics, paper, and multilayer packaging into food simulants (aqueous, acidic, alcoholic).
    • Compliance testing with GB 31604.8, EU Framework Regulation, and other global migration requirements.

    Pharmaceutical Packaging (Non‑Volatile Residue)

    • Extractables screening​ of container‑closure systems.
    • Non‑volatile residue testing​ of elastomeric closures, flexible films, and laminates per YBB standards.

    Pharmaceutical & Chemical QC (Loss on Drying)

    • Loss on Drying (LOD)​ of APIs, excipients, and bulk drugs per USP <921>​ and Ph. Eur. 2.2.32.
    • Moisture content​ determination in powders, granules, and solid dosage forms.

    Food & Beverage QC

    • Moisture analysis​ of dairy powders, starches, cereals, and dehydrated foods per GB 5009.3.
    • Total solids / dry residue​ testing of bottled water and beverages per GB 8538.

     

    Working Principle

    The ERT‑C Series executes a fully automated four‑stage constant‑weight cycle:
    1.Water‑Bath Evaporation​
    Test portions (food simulant, extract solution, or aqueous sample) are gently evaporated to near‑dryness in a controlled water bath (ambient to 100 °C). Indirect heating prevents bumping and thermal degradation.
    2.High‑Temperature Drying​
    Vessels are transferred to a precision drying chamber (ambient to 140 °C) to remove residual moisture and volatile matter.
    3.Low‑Humidity Cooling​
    Vessels are cooled in a patented chamber maintained at < 20% RH, preventing moisture reabsorption-an inherent weakness of manual desiccator methods.
    4.Constant‑Temperature Weighing​
    A METTLER TOLEDO analytical balance (0.1 mg readability)​ weighs the vessels. The system repeats the dry–cool–weigh cycle until constant weight (≤ 0.3 mg difference over two cycles)​ is achieved, then calculates residue mass, migration level, or moisture content.

     

    Compliance Standards

    ISO 759​ - Plastics - Determination of loss of volatile matter
    USP <921>​ - Loss on Drying
    Ph. Eur. 2.2.32​ - Loss on Drying
    EP 9.0​ - Water, Purified
    ASTM D5404 / ASTM D6447​ - Moisture content by oven drying
    GB 31604.8​ - Food contact materials - Determination of total migration
    GB 5009.3​ - National food safety standard - Determination of moisture in foods
    GB 8538​ - National food safety standard - Examination of drinking natural mineral waters
    GB/T 9740​ - Chemical reagents - Determination of evaporation residue
    GB/T 2914​ - Plastics - Determination of volatile matter
    GB 5413.39​ - Determination of insoluble dietary fiber in foods
    GB/T 5750.4 / DZT 0064.9 / GB/T 14415​ - Water and mineral analysis
    ChP General Provisions​ - Constant‑weight requirement
    ChP Part IV​ - Extractives determination method, Loss on Drying, Total Solids
    ChP Part II​ - Purified Water
    YBB 00342002​ - Evaporation residue of pharmaceutical packaging
    YBB 00132002​ - Non‑volatile matter of pharmaceutical packaging

     

    Key Features

    • Fully Automated 4‑in‑1 Workflow​
                Integrates water‑bath evaporation, drying, low‑humidity cooling, and weighing into a single, unattended process.
    • Pharmacopoeia‑Grade Constant Weight​
                Achieves 0.3 mg constant weight within two drying cycles, fully aligned with USP, Ph. Eur., and ChP requirements.
    • Scalable Workstation Configurations​
                Available with 12, 18, or 23 workstations, supporting small to medium‑scale QC and research laboratories.
    • Patented Balance Protection​
                Thermal isolation, moisture‑proofing, and anti‑corrosion technologies protect the METTLER TOLEDO balance​ from heat, vapor, and corrosive residues.
    • Low‑Humidity Cooling Chamber​
                Maintains <20% RH​ during cooling, eliminating moisture reabsorption errors common in manual methods.
    • Safe & Reliable Operation​
                Indirect heating, over‑temperature power‑off protection, and water‑level monitoring ensure safe handling of flammable solvents and acidic simulants.
    • Dual Test Modes​
         Constant‑Weight Mode​ (auto‑terminates at ≤ 0.3 mg) and Constant‑Time Mode​ (fixed drying duration).
    • GMP‑Ready (Optional)​
                Optional Computerized System Module​ provides user management, electronic signatures, and audit trails compliant with 21 CFR Part 11​ and NMPA GMP.
    • High‑Efficiency Solvent Recovery (Optional)​
                Captures up to 95%​ of evaporated solvents (ethanol, acetic acid), reducing waste disposal costs and VOC emissions.

     

    Technical Specifications

     

    Name

    Parameter

    Name

    Parameter

    Constant Weight Error0.3 mg  (2 heating cycles)Residue Range0 ~ 80g
    Balance Range220 gBalance readability0.1 mg
    Temperature Error0.5 °CEvaporating TemperatureRoom Temp ∼ 100 °C
    Drying TemperatureRoom Temp ∼ 140 °CWeighing TemperatureRoom Temp ∼ 80 °C
    Evaporite ModeWater BathWeighing R.Humidity<20%
    Evaporating utensil capacity100mL (Optional: 50/200mL)Connect Pipe¢8mm
    Air Pressure>0.3MpaSolvent Recovery Rate95%  
    Power SupplyAC220/110V; 50/60Hz  

    Model

    Model Number

    ERT-121-C

    ERT-181-C

    ERT-231-C

    Specimen Number

    12

    18

    23

    Quantity of Balances

    1

    1

    1

    Net Weight

    ~150KGS

    ~154KGS

    ~290KGS

    Size860x750x690mm (LxBxH)
    Power Consumption<10KW
     

    Standard Configuration

    Main testing unit (host)
    Drying system
    Evaporating vessels (12 / 18 / 23 pcs respectively)
    Test computer with professional software
    METTLER TOLEDO analytical balance (0.1 mg)
    Valve suites

    Optional Accessories

    High‑Efficiency Solvent Recovery Device
    0.01 mg Analytical Balance
    GMP Computerized System Module
    Alternative evaporating vessels (50 mL / 200 mL)

    User‑Provided Items

    Compressed air source (> 0.3 MPa)
    Distilled water
    Tap water

     

    Frequently Asked Questions (FAQ)

    Q1: What is the main application of the ERT‑C Series?
    A: The ERT‑C Series is purpose‑built for total migration testing (GB 31604.8), non‑volatile residue testing (YBB), and loss on drying / moisture analysis (USP <921>, Ph. Eur. 2.2.32). It is not intended for high‑temperature ashing or ash content determination.
    Q2: How does this instrument replace a water bath, oven, and balance?
    A: It integrates all three functions into one system. Samples are evaporated, dried, cooled under low humidity, and weighed automatically-eliminating manual transfer and moisture reabsorption errors associated with desiccators.
    Q3: What does “0.3 mg constant weight” mean?
    A: Pharmacopoeias define constant weight​ as successive weighings differing by no more than 0.3 mg. The ERT‑C automatically repeats the dry–cool–weigh cycle until this criterion is met, ensuring regulatory compliance.
    Q4: Why is low‑humidity cooling important for total migration testing?
    A: After drying, residues readily reabsorb moisture from ambient air. The ERT‑C cools samples in a <20% RH chamber, stabilizing the residue mass before weighing-critical for accurate migration and LOD results.
    Q5: Can the ERT‑C handle alcoholic food simulants?
    A: Yes. The instrument is compatible with aqueous and alcoholic simulants. For ethanol‑based methods, the optional solvent recovery device​ is strongly recommended to control VOC emissions.
    Q6: How do I choose between the 12, 18, and 23 workstation models?
    A: Selection depends on daily throughput:
          ERT‑121‑C: Low‑volume QC or R&D
          ERT‑181‑C: Medium‑scale routine testing
          ERT‑231‑C: High‑volume QC laboratories

     

     

  • Functions

    Constant weight tests for loss on drying, non - volatile substances, residue quantity, total migration, volatile substances, moisture content, soluble and insoluble quantities.

    It can replace water baths, drying ovens and balances to achieve constant weight .

  • Constant weighting requirement in Chinese Pharmacopoeia, Extractives Determination Method" in Part Four of the Chinese Pharmacopoeia、Loss on Drying Determination Method、Total Solids Determination Method、USP40-NF35<921>、YBB 00342002、YBB00132002、GB 31604.8、GB5009.3、GB 8538、DZT0064.9、GBT14415、GBT5750.4、GB/T 9740、GB/T2914、GB5413.39、ISO 759、"Purified Water" in Part Two of the Chinese Pharmacopoeia、EP9.0 WATER, PURIFIED

  • Features

    • Complies with national standards and features a fully automated four-process system: water bath, drying, cooling, and weighing.
    • Precise and efficient: Achieves 0.3mg constant weight with just 2 drying cycles. Available with 12、18, 23, 33, 46, or 69 workstations.
    • Safe: Indirect heating design to prevent combustion and explosion. Equipped with over temperature power off protection and water level protection.
    • Compact: Water bath chamber, drying oven, cooling unit and weighing balance are integrated into one unit, footprint reduction.
    • Features patented: heat insulation, moisture proof, and anti-corrosion technology for the balance, ensuring its stability and long service life.
    • Digitally set test parameters, fully automated operation without manual intervention. Offers two test modes: constant weight and constant time.
    • Equipped with METTLER TOLEDO balance.
    • Software: Provides graphical, full process and all element monitoring, along with multiple report formats.
    • Optional: GMP "Computerized System" functional module.
    • Optional: High - efficiency solvent recovery device.
  • Specification

    Name

    Parameter

    Name

    Parameter

    Constant Weighting Error

    0.3 mg

    (2 heating cycles)

    Residue Range

    0~80 g

    Balance Range

    210 g

    Balance resolution

    0.1 mg

    Temperature Error

    0.5 ℃

    Evaporating Temperature

    Room Temperature ~100 ℃

    Drying Temperature

    Room Temperature~140 ℃

    Weighing Temperature

    room~80 ℃

    Evaporite Mode

    Water bath

    Weighing humidity

    <20%

    Evaporating utensil capacity

    100 mL

    (Optional: 50, 200 mL)

    Connect Pipe

    Φ8 mm

    Air Pressure

    >0.3 MPa

    Solvent Recovery Rate

    95%  (Optional: Solvent Recovery Machine)

    Power Supply

    AC220V /110V ;50/60Hz 

     

     

    Model

    Model

    ERT-91-C

    ERT-121-C

    ERT-181-C

    Specimen Count

    12

    18

    23

    Balance Count

    1

    1

    1

    Net Weight

    ~150kg

    ~154kg

    ~290kg

    Size  (L×B×H) mm

    860×750×690

    Power Consumption

    <10,000 W

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    • Configuration: Principal Machine, Dryer Machine, Evaporating Utensil, Computer, Professional software, Valve Suits.
    • Optional: Solvent Recovery Machine、0.01mg balance.
    • Self-provided: Compressed air、Distilled water, tap water..

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