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Key: test item, instrument name, total nonvolatile migration, gravimeter, moisture permeameter
Loss on drying
Release time:
2021-08-05
Pharmaceuticals is a very rigorous process, and the quality of raw materials has a major impact on the quality of pharmaceuticals. In this regard, the state has formulated a number of testing items to identify the quality of raw materials, and "loss on drying" is one of them.
According to the pharmacopoeia, take about 1g or the weight specified under each item, place it in a flat weighing bottle that is dried to a constant weight under the same conditions as the test product, and accurately weigh it. Unless otherwise specified, dry at 105℃ to a constant weight. Calculate the loss on drying of the test product from the lost weight and the sample volume.
Ovens and balances are routine instruments in the laboratory. The experimental process is not difficult at first glance, but it is always tricky in actual work. First of all, a 1g sample often contains very little water, and it is easily affected by environmental humidity when the experimenter manually operates it. In addition, according to the requirements of the pharmacopoeia, the difference in weighing after 2 times of drying is less than 0.3mg for a constant weight. This puts forward higher requirements for manual operation, so it often takes a long time for experimenters to complete the experiment, and it even appears that the quality after drying is heavier than the quality before drying.
Is there an easier way to detect this item? The answer is yes-Constant Weight Tester.
The constant weight instrument developed and designed by Xitang Technology specifically to meet the requirements of constant weight, integrates heating and drying, drying and cooling, constant temperature weighing and other functions. Instead of traditional ovens, drying ovens and balances, two weighing processes can achieve constant weight weighing. It not only perfectly meets the requirements of the standard 100%, but also greatly improves the efficiency of constant weight and the accuracy of the experiment.
At this point, the "loss on drying" experiment does not need to waste more time, the experimenter only needs to load the sample, and the rest is handed over to the automation. At present, more than ten listed pharmaceutical companies have applied the constant weight instrument for quality inspection.
In addition, the constant weight meter is also equipped with a water bath function. In addition to the drying weight loss test, it can also be used for: non-volatile matter in purified water, non-volatile matter in extracts of medicine packaging materials, extracts of traditional Chinese medicines and other experiments that require constant weight.
Loss on Drying Constant Weight——Relative Products:
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