Key: test item, instrument name, total nonvolatile migration, gravimeter, moisture permeameter
Product
Water Bath Drying Constant Weight Analyzer
- Description
- Applications
- Standard
- Features
- Parameter
- Configuration
- Video
- PDF Download
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- Commodity name: Water Bath Drying Constant Weight Analyzer
ERT-231 /331 /461 /691 -C
Water Bath Constant‑Weight Analyzer for Total Migration & Loss on Drying
ERT‑C Series (Automated Evaporation‑Drying‑Weighing Workstation)
Overview
The LabStone ERT‑C Series is a fully automated workstation designed to replace the traditional, labor‑intensive workflow of water baths, drying ovens, desiccators, and analytical balances. It is engineered for high‑throughput total migration testing, non‑volatile residue determination, and loss on drying / moisture analysis across pharmaceuticals, food contact materials, and chemicals.By integrating water‑bath evaporation, precision drying, low‑humidity cooling, and analytical weighing into a single system, the ERT‑C Series delivers regulatory‑grade constant‑weight results with minimal operator intervention.Key Applications
Food Contact Materials
- Total Migration Testing: Gravimetric determination of migrants from plastics, paper, and multilayer packaging into food simulants (aqueous, acidic, alcoholic, and fatty).
- Screening of New Formulations: Rapid evaluation of resin and additive impacts on migration performance.
Pharmaceutical & Biopharma
- Extractables & Leachables (E&L): Non‑volatile residue profiling of container‑closure systems.
- Loss on Drying (LOD): Water content determination in APIs, excipients, and bulk drugs.
- Packaging Safety: Compliance verification for elastomeric closures and flexible films.
Food & Beverage QC
- Moisture Analysis: Grains, dairy powders, starches, and dehydrated products.
- Total Solids / Dry Residue: Bottled water, beverages, and liquid ingredients.
Chemicals & Polymers
- Evaporation Residue: Resins, solvents, and chemical intermediates.
- Volatile Matter: Plastics, rubber, and synthetic polymers.
Working Principle
The ERT‑C Series executes a fully automated four‑stage constant‑weight cycle:Water‑Bath EvaporationTest portions are gently evaporated to near‑dryness in a controlled water bath (ambient to 100 °C). Indirect heating prevents bumping and thermal degradation.High‑Temperature DryingVessels are transferred to a precision drying chamber (ambient to 140 °C) to remove residual moisture and volatile matter.Low‑Humidity CoolingVessels are cooled in a patented chamber maintained at < 20% RH, preventing moisture reabsorption-an inherent weakness of manual desiccator methods.Constant‑Temperature WeighingA METTLER TOLEDO analytical balance (0.1 mg readability) weighs the vessels. The system repeats the dry–cool–weigh cycle until constant weight (≤ 0.3 mg difference over two cycles) is achieved.
Compliance Standards
ISO 759 - Plastics - Determination of loss of volatile matterASTM D5404 / ASTM D6447 - Standard practices for moisture content by oven dryingUSP <921> - Loss on DryingPh. Eur. 2.2.32 - Loss on DryingEP 9.0 - Water, PurifiedGB 31604.8 - Food contact materials - Determination of total migrationGB 5009.3 - National food safety standard - Determination of moisture in foodsGB 8538 - National food safety standard - Examination of drinking natural mineral watersGB/T 9740 - Chemical reagents - General method for determination of evaporation residueGB/T 2914 - Plastics - Determination of volatile matterGB 5413.39 - Determination of insoluble dietary fiber in foodsGB/T 5750.4 / DZT 0064.9 / GB/T 14415 - Water and mineral analysisChP General Provisions - Constant‑weight requirementChP Part IV - Extractives determination method, Loss on Drying, Total SolidsChP Part II - Purified WaterYBB 00342002 - Evaporation residue of pharmaceutical packagingYBB 00132002 - Non‑volatile matter of pharmaceutical packagingKey Features
Fully Automated 4‑in‑1 WorkflowIntegrates evaporation, drying, cooling, and weighing into a single, unattended process.Pharmacopoeia‑Grade Constant WeightAchieves 0.3 mg constant weight within two drying cycles, fully aligned with USP, Ph. Eur., and ChP requirements.Scalable High‑Throughput ConfigurationsAvailable with 23, 33, 46, or 69 workstations and 1–3 METTLER TOLEDO balances, supporting batch testing of large sample sets.Patented Balance ProtectionThermal isolation, moisture‑proofing, and anti‑corrosion technologies protect the balance from heat, vapor, and corrosive residues.Low‑Humidity Cooling ChamberMaintains < 20% RH during cooling, eliminating moisture reabsorption errors common in manual methods.Safe & Reliable OperationIndirect heating, over‑temperature power‑off protection, and water‑level monitoring ensure safe handling of flammable solvents and acidic simulants.Dual Test ModesConstant‑Weight Mode (auto‑terminates at ≤ 0.3 mg) and Constant‑Time Mode (fixed drying duration).GMP‑Ready (Optional)Optional Computerized System Module provides user management, electronic signatures, and audit trails compliant with 21 CFR Part 11 and NMPA GMP.High‑Efficiency Solvent Recovery (Optional)Captures up to 95% of evaporated solvents (ethanol, acetic acid), reducing waste disposal costs and VOC emissions.Technical Specifications
Name
Parameter
Name
Parameter
Constant Weighting Error
0.3 mg (2 heating cycles)
Residue Range
0~80 g
Balance Range
210 g
Balance resolution
0.1 mg
Temperature Error
0.5 ℃
Evaporating Temperature
RT ~100 ℃
Drying Temperature
RT~140 ℃
Weighing Temperature
RT~80 ℃
Evaporite Mode
Water bath
Weighing humidity
<20%
Evaporating utensil capacity
100 mL(Optional: 50, 200 mL)
Connect Pipe
Φ8 mm
Air Pressure
>0.3 MPa
Solvent Recovery Rate
95%
Power Supply
AC220V /110V ;50/60Hz
Model
Model
ERT-231-C
ERT-331-C
ERT-462-C
ERT-693-C
Specimen Count
23
33
46
69
Balance Count
1
1
2
3
Size (L×B×H) mm
1300x870x1160 mm
Net Weight
~170kg
~175kg
~180kg
~185kg
Power Consumption
<10,000 W
Standard Configuration
Main testing unit (host)Drying systemEvaporating vessels (quantity per model)Test computer with professional softwareMETTLER TOLEDO analytical balance (0.1 mg)Valve suitesOptional Accessories
High‑Efficiency Solvent Recovery Device0.01 mg Analytical BalanceGMP Computerized System ModuleAlternative evaporating vessels (50 mL / 200 mL)User‑Provided Items
Compressed air source (> 0.3 MPa)Distilled waterTap waterFrequently Asked Questions (FAQ)
Q1: How does the ERT‑C Series differ from a conventional drying oven?A: Conventional ovens only dry samples. After drying, samples must be manually transferred to a desiccator and weighed-a process prone to moisture reabsorption and operator variability. The ERT‑C integrates evaporation, drying, low‑humidity cooling, and weighing into a single automated cycle, ensuring true constant‑weight compliance with pharmacopoeia requirements.Q2: What does “0.3 mg constant weight” mean?A: Pharmacopoeias define constant weight as successive weighings differing by no more than 0.3 mg. The ERT‑C automatically repeats the dry–cool–weigh cycle until this criterion is met, eliminating subjective judgment and ensuring regulatory compliance.Q3: Can this instrument perform total migration testing with alcoholic simulants?A: Yes. The ERT‑C is fully compatible with aqueous and alcoholic simulants. For ethanol‑based methods, the optional solvent recovery device is strongly recommended to manage VOC emissions and reduce hazardous waste.Q4: Why is low‑humidity cooling important?A: After drying, hot residues rapidly reabsorb moisture from ambient air. The ERT‑C cools samples in a < 20% RH chamber, stabilizing the residue mass before weighing-critical for trace‑level residue and moisture determinations.Q5: How do I choose the right model?A: Selection depends on daily sample throughput:ERT‑231‑C: Small QC labs (~20 samples/day)ERT‑331‑C: Medium‑scale testingERT‑462‑C: High‑volume QC and contract labsERT‑693‑C: Large contract research organizations and national testing institutesQ6: What is the difference between the ERT‑C Series and the IRT Series?A: The ERT‑C Series is designed for low‑temperature applications (≤ 140 °C): total migration, non‑volatile residue, and loss on drying. The IRT Series is designed for high‑temperature ashing (up to 1000 °C): ignition residue, ash content, and loss on ignition. They are complementary systems for different gravimetric methods. -
Functions
Constant weight tests for loss on drying, non - volatile substances, residue quantity, total migration, volatile substances, moisture content, soluble and insoluble quantities.
It can replace water baths, drying ovens and balances to achieve constant weight .
Principle
Water bath evaporation; high temperature drying; drying and cooling; constant temperature weighing.
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Standards:
Constant weighting requirement in Chinese Pharmacopoeia, Extractives Determination Method" in Part Four of the Chinese Pharmacopoeia、Loss on Drying Determination Method、Total Solids Determination Method、USP40-NF35<921>、YBB 00342002、YBB00132002、GB 31604.8、GB5009.3、GB 8538、DZT0064.9、GBT14415、GBT5750.4、GB/T 9740、GB/T2914、GB5413.39、ISO 759、"Purified Water" in Part Two of the Chinese Pharmacopoeia、EP9.0 WATER, PURIFIED
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Features
- Complies with national standards and features a fully automated four-process system: water bath, drying, cooling, and weighing.
- Precise and efficient: Achieves 0.3mg constant weight with just 2 drying cycles. Available with 12、18, 23, 33, 46, or 69 workstations.
- Safe: Indirect heating design to prevent combustion and explosion. Equipped with over temperature power off protection and water level protection.
- Compact: Water bath chamber, drying oven, cooling unit and weighing balance are integrated into one unit, footprint reduction.
- Features patented: heat insulation, moisture proof, and anti-corrosion technology for the balance, ensuring its stability and long service life.
- Digitally set test parameters, fully automated operation without manual intervention. Offers two test modes: constant weight and constant time.
- Equipped with METTLER TOLEDO balance.
- Software: Provides graphical, full process and all element monitoring, along with multiple report formats.
- Optional: GMP "Computerized System" functional module.
- Optional: High - efficiency solvent recovery device.
- Complies with national standards and features a fully automated four-process system: water bath, drying, cooling, and weighing.
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Specification
Name
Parameter
Name
Parameter
Constant Weighting Error
0.3 mg
(2 heating cycles)
Residue Range
0~80 g
Balance Range
210 g
Balance resolution
0.1 mg
Temperature Error
0.5 ℃
Evaporating Temperature
Room Temperature ~100 ℃
Drying Temperature
Room Temperature~140 ℃
Weighing Temperature
room~80 ℃
Evaporite Mode
Water bath
Weighing humidity
<20%
Evaporating utensil capacity
100 mL
(Optional: 50, 200 mL)
Connect Pipe
Φ8 mm
Air Pressure
>0.3 MPa
Solvent Recovery Rate
95% (Optional: Solvent Recovery Machine)
Power Supply
AC220V /110V ;50/60Hz
Model
Model
ERT-231-C
ERT-331-C
ERT-462-C
ERT-693-C
Specimen Count
23
33
46
69
Balance Count
1
1
2
3
Size (L×B×H) mm
1300x870x1160 mm
Net Weight
~170kg
~175kg
~180kg
~185kg
Power Consumption
<10,000 W
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Configuration: Principal Machine, Dryer Machine, Evaporating Utensil, Computer, Professional software, Valve Suits.
Optional: Solvent Recovery Machine、0.01mg balance.
Self-provided: Compressed air、Distilled water, tap water..
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